diff --git a/changelogs/fragments/6522-copr-respawn.yaml b/changelogs/fragments/6522-copr-respawn.yaml
new file mode 100644
index 0000000000..8d5922e4c9
--- /dev/null
+++ b/changelogs/fragments/6522-copr-respawn.yaml
@@ -0,0 +1,4 @@
+---
+minor_changes:
+  - "copr - respawn module to use the system python interpreter when the ``dnf`` python module is not available in ``ansible_python_interpreter``
+    (https://github.com/ansible-collections/community.general/pull/6522)."
diff --git a/plugins/modules/copr.py b/plugins/modules/copr.py
index 965c2a935d..1311de849d 100644
--- a/plugins/modules/copr.py
+++ b/plugins/modules/copr.py
@@ -97,6 +97,7 @@ except ImportError:
     DNF_IMP_ERR = traceback.format_exc()
     HAS_DNF_PACKAGES = False
 
+from ansible.module_utils.common import respawn
 from ansible.module_utils.six.moves.urllib.error import HTTPError
 from ansible.module_utils.basic import missing_required_lib
 from ansible.module_utils import distro  # pylint: disable=import-error
@@ -104,6 +105,20 @@ from ansible.module_utils.basic import AnsibleModule  # pylint: disable=import-e
 from ansible.module_utils.urls import open_url  # pylint: disable=import-error
 
 
+def _respawn_dnf():
+    if respawn.has_respawned():
+        return
+    system_interpreters = (
+        "/usr/libexec/platform-python",
+        "/usr/bin/python3",
+        "/usr/bin/python2",
+        "/usr/bin/python",
+    )
+    interpreter = respawn.probe_interpreters_for_module(system_interpreters, "dnf")
+    if interpreter:
+        respawn.respawn_module(interpreter)
+
+
 class CoprModule(object):
     """The class represents a copr module.
 
@@ -460,6 +475,7 @@ def run_module():
     params = module.params
 
     if not HAS_DNF_PACKAGES:
+        _respawn_dnf()
         module.fail_json(msg=missing_required_lib("dnf"), exception=DNF_IMP_ERR)
 
     CoprModule.ansible_module = module
diff --git a/tests/integration/targets/copr/tasks/main.yml b/tests/integration/targets/copr/tasks/main.yml
index 0e46517240..0d66378112 100644
--- a/tests/integration/targets/copr/tasks/main.yml
+++ b/tests/integration/targets/copr/tasks/main.yml
@@ -10,12 +10,6 @@
       ansible_distribution == 'Fedora'
       or (ansible_os_family == 'RedHat' and ansible_distribution != 'Fedora'
           and ansible_distribution_major_version | int >= 8)
-    # The copr module imports dnf which is only available for the system Python
-    # interpreter.
-    - >
-      not (ansible_distribution == 'CentOS' and
-           ansible_distribution_major_version | int == 8 and not
-           ansible_python_version.startswith('3.6'))
   block:
   - debug: var=copr_chroot
   - name: enable copr project