diff --git a/changelogs/fragments/4151-dconf-catch-psutil-nosuchprocess.yaml b/changelogs/fragments/4151-dconf-catch-psutil-nosuchprocess.yaml
new file mode 100644
index 0000000000..6856af8a28
--- /dev/null
+++ b/changelogs/fragments/4151-dconf-catch-psutil-nosuchprocess.yaml
@@ -0,0 +1,2 @@
+bugfixes:
+  - "dconf - skip processes that disappeared while we inspected them (https://github.com/ansible-collections/community.general/issues/4151)."
diff --git a/plugins/modules/system/dconf.py b/plugins/modules/system/dconf.py
index f7776cde6e..636ca536ee 100644
--- a/plugins/modules/system/dconf.py
+++ b/plugins/modules/system/dconf.py
@@ -180,9 +180,9 @@ class DBusWrapper(object):
         self.module.debug("Trying to detect existing D-Bus user session for user: %d" % uid)
 
         for pid in psutil.pids():
-            process = psutil.Process(pid)
-            process_real_uid, dummy, dummy = process.uids()
             try:
+                process = psutil.Process(pid)
+                process_real_uid, dummy, dummy = process.uids()
                 if process_real_uid == uid and 'DBUS_SESSION_BUS_ADDRESS' in process.environ():
                     dbus_session_bus_address_candidate = process.environ()['DBUS_SESSION_BUS_ADDRESS']
                     self.module.debug("Found D-Bus user session candidate at address: %s" % dbus_session_bus_address_candidate)
@@ -198,6 +198,9 @@ class DBusWrapper(object):
             # This can happen with things like SSH sessions etc.
             except psutil.AccessDenied:
                 pass
+            # Process has disappeared while inspecting it
+            except psutil.NoSuchProcess:
+                pass
 
         self.module.debug("Failed to find running D-Bus user session, will use dbus-run-session")